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$ (i\gamma_\mu \partial^\mu - m ) \Psi =0 $
The Dirac equation describes how the state of a relativistic (= fast moving) quantum system with half-integer spin changes in time.
The analogous equation for systems without spin is the Klein-Gordon equation.
If the system only moves slowly, the Dirac equation becomes the Pauli equation.
Gamma Gymnastics:
There are many important rules for the $\gamma$ matrices that appear in the Dirac equation. These rules are important for many practical calculations.
Graphical Summary
The diagram below shows the Dirac equation and its Lagrangian in various forms. For a more detailed explanation see Fun with Symmetry.